A series of loud explosions are heard in central Israel as the military says it carried out intelligence-based strikes in Tehran.

View of Tel Aviv skyline as Israel strikes Iran’s nuclear sites and kills top generals ISRAEL has launched devastating air strikes against Iran in a dramatic escalation risking all-out nuclear war in the Middle East.

Iran fired a new wave of missiles at Israel on Saturday, injuring several people in residential buildings, as Israel said it was striking Tehran in response.

The Iranian and Israeli strikes mark the most sustained, direct attacks ever between the two rivals. Three people were killed in Israel and at least 78 in Iran, officials said.

At least two people have been killed in Israel following multiple rounds of Iranian airstrikes in retaliation for missiles launched during "Operation Rising Lion." Israeli Defense Minister Israel Katz said Saturday that "If Khamenei continues to fire missiles at Israel’s home front – Tehran will burn.

Fox News, The New York Times report Iranian missile hit tower in 'Kirya' Defense Ministry complex - Anadolu Ajansı

The attacks, which Israel said targeted Iran’s nuclear program and military targets, killed Maj. Gen. Hossein Salami, head of Iran’s Islamic Revolutionary Guard Corps.

It contains a range of sophisticated centrifuges, including the most advanced models, for enriching uranium to high levels. The International Atomic Energy Agency, the U.N. nuclear watchdog, says there are nearly 14,000 centrifuges at work there, with thousands more in place but inactive.

Video verified by CNN captures the dramatic moment a missile struck in vicinity of the Kirya, an area of Tel Aviv that’s home to an urban military base housing Israel’s Defense Forces.