Christina Applegate was diagnosed with multiple sclerosis (MS) in 2021 and has since spoken about the debilitating disease.

Christina Applegate's raw memoir, 'You With the Sad Eyes,' chronicles childhood trauma, sexual abuse and struggles with MS.

Amid her journey with multiple sclerosis, Christina Applegate shared that she’s bedridden for most of her days.

Christina Applegate didn't "look in the mirror for a year" after dropping 50 pounds amid her battle with MS, RadarOnline.com can reveal. The weight loss she endured was so significant that Applegate ...

The “Married … With Children” star was just 36 when a routine MRI in 2008 revealed early-stage breast cancer. Finding out she ...

Some days I can bear to dance, others I fear the wheelchair," Applegate writes in her new memoir, "You With the Sad Eyes." ...

In her wide-ranging interview with Roberts, Applegate also touched on her willingness to return to acting. Applegate was diagnosed with MS while starring in her last major acting role, Netflix's "Dead ...

Christina Applegate is now practically bedridden as movement has become increasingly painful as she battles multiple ...

Applegate recalled there were some less obvious signs that she had been ignoring, in the run up to her diagnosis. According ...

In her new memoir, the actor’s candid descriptions of how she’s faring with her multiple sclerosis make me feel seen and ...

Christina Applegate reveals how multiple sclerosis has impacted her parenting of 15-year-old daughter, sharing raw details ...

It was like having a therapy session, and I couldn't stop,” Christina Applegate says of her memoir. The book's honesty leaves ...