The 49ers ruled out Brock Purdy for the fourth time this season and plan to have Mac Jones start Sunday’s visit to Tampa Bay.

The injury report for the Tampa Bay Buccaneers (4-1) heading into their game against the San Francisco 49ers (4-1) features 11 players. The contest starts at 4:25 p.m. ET on Sunday, Oct. 12, at Raymond James Stadium. Game time: 4:25 p.m. ET

A new report from an NFL insider indicates that the San Francisco 49ers are interested in potentially acquiring Trey Hendrickson.

Mac Jones, already battered through three starts, was sacked six times and intercepted twice but threw for 347 yards with a sore oblique and knee. Coach Kyle Shanahan didn’t blame Jones for getting intercepted on the opening possession’s third down, seeing how Kendrick Bourne apparently turned the wrong way on his route.

With Fred Warner joining Nick Bosa on the sidelines, the San Francisco 49ers are turning to their first-year defensive players. That didn't work out well Sunday in Tampa.

The San Francisco 49ers had some good news on their Week 6 injury report, but it still highlights a slew of problems on the health front as they enter a Week 6 showdown vs. the Tampa Bay Buccaneers.

The San Francisco 49ers are far away from discussing their draft plans, but it is never too early to look into what the roster may look like moving forward. Bleacher Report ranked the draft needs for every team, and they were close to the mark with the 49ers. They put tackle first, then wide receiver and guard third.

The NFL has announced a punishment for a San Francisco 49ers star following the team’s recent loss to the Tampa Bay Buccaneers.

The Cincinnati Bengals don't plan to trade defensive end Trey Hendrickson at this time, despite interest from San Francisco, according to ESPN.