The San Francisco 49ers are about to gear up for their first game without their biggest star, Fred Warner. The season hangs in the balance following this injury, and even though key players on both sides of the ball are set to return in the coming weeks, the absence of Fred Warner and Nick Bosa will still leave a massive void on defense.

The San Francisco 49ers are hoping to get both quarterback Brock Purdy and wide receiver Ricky Pearsall back for the Week 8 contest against the Houston Texans. Here's what we know about their chances of returning from injury.

While the 49ers have dealt with as many key injuries as any team in the league, the Falcons have been relatively healthy so far this year. Atlanta did lose starting right tackle Kaleb McGary for the season back in August, but this team should otherwise be close to full strength for tonight's game.

The San Francisco 49ers plan all along was to get a lot younger at key areas while also keeping the window open with an aging roster. They currently sit at 4-2, and while things could be going better for their 2025 outlook, the rookie class is doing exactly what the team needed them to.

For the 49ers, according to NFL insider Dianna Russini of The Athletic, the 49ers are the top team vying for Hendrickson, as they're "showing the most interest" in the All-Pro pass rusher ahead of the trade deadline.

The San Francisco 49ers have lost Fred Warner for the year, but defensive coordinator Robert Saleh believes Tatum Bethune is the right man to fill in.