At the end of the 4-cell stage, embryos divide to the 8-cell stage, forming many different shapes and high variability between embryos. Then, cells increase their surface tension which brings cells ...

Live imaging of embryos at different stages. Chromosomes are labeled in magenta. 4-cell sister blastomeres are shown, along with 3D-reconstructed images of 2-to-4-cell and 4-to-8-cell divisions.

Embryo development starts when a single egg cell is fertilized and starts dividing continuously. Initially a chaotic cluster, it gradually evolves into a highly organized structure. Scientists have ...

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication. Led by Ichiro Hiratani and colleagues, the ...

The curved shape of a zebrafish egg causes unequal cell divisions, creating larger cells near the animal pole and smaller cells at the margin—a size gradient that controls the timing of everything ...

Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...

A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...