AMP-activated protein kinase (AMPK) occurs as heterotrimeric protein complexes that monitor cellular energy status by sensing the concentrations of ATP, ADP and AMP. Displacement of ATP by ADP or AMP ...

AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even those that do not disrupt the ...

Researchers have developed a new system that lets them study in more detail than ever exactly how, where and when the metabolic protein AMPK carries out its molecular and therapeutic functions. The ...

Discover how exercise reduces the risk of diseases by triggering a hormetic response in our cells and enhancing mitochondrial ...

Researchers have discovered that salicylate, the active ingredient in aspirin, directly increases the activity of the protein AMPK (AMP-activated protein kinase), a key player in regulating cell ...

The transcription factor sex-determining region Y-related high-mobility group-box gene 9 (SOX9) plays a critical role in organ development. Although SOX9 has been implicated in regulating lipid ...

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream activation by the kinase LKB1 is well recognized, the ...

Berberine, a bioactive alkaloid derived from various plants, including Berberis species, has garnered significant attention as a nutraceutical agent due to its potential benefits in metabolic health.

Coffee has been linked to longevity in past studies, with some suggesting that 3 cups is the magic number for living longer. A new study published in Microbial Cell found that the caffeine in coffee ...

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals advances ...

Forget wrinkle creams and superfoods, the secret to anti-aging may already be in your kitchen. Scientists at Queen Mary University of London have discovered that caffeine could be nudging your cells ...