The Allen Mouse Brain Common Coordinate Framework (CCFv3), a 3D reference atlas, is based on an average of the inherent fluorescence in the brains of mice imaged using serial two-photon tomography.
“No one has ever taken this kind of industrial approach to surveying the active brain at cellular resolution in order to measure how the brain processes information in real time,” Christof Koch, ...
Registration of the MERFISH-derived cell atlas to the Allen Mouse Brain Common Coordinate Framework allows systematic quantification of cell-type composition and organization in every brain region ...
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