Activity–dependent changes in synaptic strength, such as long–term potentiation (LTP), are believed to be critical for information processing in the mature brain and for the refinement of neuronal ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

One of the earliest signs of amyloid-β (Aβ) toxicity is synaptic loss, and recent work from a number of labs has shown that Aβ causes depressed synaptic transmission due to removal of cell surface ...

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment ...

D epression can be challenging to treat. Typical antidepressants, which affect levels of chemicals in the brain involved in mood regulation, have been evolving for decades. But recent findings ...

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A new study suggests a potential molecular strategy for treating fragile X syndrome, an inherited neurodevelopmental disorder that causes autism spectrum disorder and intellectual disability. This ...

Please provide your email address to receive an email when new articles are posted on . Cognitive recovery was greatest within the first 6 months of diagnosis, persisting up to 36 months. After the 36 ...

An earlier study showed that ketamine, used experimentally, kicked depression in hours instead of weeks. This study showed that a boost in the AMPA receptor is a necessary ingredient. The glutamate ...

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in ...

In February 2025, Ryan Alto, a 48-year-old from California, developed what seemed like a routine flu. He had a headache, body aches, and general fatigue, but within hours of driving himself to the ...