The coagulation cascade is a finely balanced system essential for maintaining haemostasis, yet its disruption can lead to either a propensity for bleeding or an increased risk of clot formation.

Although practice guidelines such as those from SurvivingSepsis.org have helped to reduce mortality and complications, sepsis ...

COVID-19 infection is associated with ischemic and hemorrhagic spinal stroke, with distinct clinical characteristics and underlying mechanisms.

Studies by researchers at Columbia University Irving Medical Center suggest that one of the immune system’s oldest branches, the complement system, and coagulation dysfunction, may be influencing the ...

An in-depth review article describing coronavirus disease 2019 (COVID-19)-related coagulopathy has recently been published in the journal Nature Reviews Immunology. Hyperinflammation and ...

Hemostasis is a complex system composed of many procoagulant and regulatory pathways. Multiple pathways, such as the intrinsic pathway, platelet activation and the tissue factor pathway, can affect ...

February 6, 2007 (Seattle, WA) - Variants in key coagulation and anticoagulation proteins were more common in postmenopausal women who developed venous thrombosis (VT) than in those who did not, ...

Uncontrolled bleeding during surgery remains one of the deadliest medical emergencies. Injuries to internal organs such as ...

A new pathway in the body that stimulates liver repair has been uncovered by researchers. Using an experimental model of high-dosage acetaminophen, the team found that liver injury activated blood ...

As people age they become more prone to blood clotting diseases, which can be caused when blood platelets clump together. This clumping can lead to strokes and cardiovascular disease. For decades, ...

Inflammatory bowel disease, in which the immune system attacks the gut, is a painful chronic condition that affects three million Americans. Rates of IBD are rising, and there's currently no cure. IBD ...