Cancer research, drug safety testing and aging biology may all gain a major boost from a new fluorescent sensor developed at Utrecht University. This new tool allows scientists to watch DNA damage and ...

A research team has successfully identified a novel DNA damage repair pathway in human cells. This study is the first to discover that proteins present in the nuclear membrane of cells directly ...

Newborn mice neurons can snap both DNA strands to migrate, then repair the breaks within a day. The process may be a normal part of brain development.

Damaged DNA can escape from one human cell and infiltrate another. Like prisoners tunneling out of jail, this DNA travels via tubelike structures between neighboring cells, scientists report May 19 in ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

Newborn nerve cells must squeeze through crowded, narrow spaces-through dense tissue, past other cells, between fibers-to reach the areas where they form neural circuits in the brain cortex. In a new ...

A drug that has passed phase 1 trials for spinal injuries in people repaired DNA breaks and reduced inflammation in mouse ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive ...

The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the ...

Researchers at the University of Liverpool have discovered that SYCP1, a protein previously thought to function only during ...

Glioblastoma multiforme is characterised by rampant genomic instability and resistance to conventional chemoradiation, driven in part by a hyperactive DNA damage response (DDR). In normal cells, ...