Researchers created a tool capable of comprehensively mapping crucial interactions underlying drug efficacy in one superfamily of cell receptors. One in every three FDA-approved drugs targets a single ...

Scientists have discovered a new generation of angiotensin receptor blockers that may be used to treat coronavirus disease 2019 (COVID-19). In silico docking and molecular dynamics studies have shown ...

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - ...

A new study has revealed the mechanism of multimerization — the association of different molecules to form complex structures ...

Deciphering how the GR forms oligomers—through the binding of several subunits—opens a crucial avenue for developing more ...

Enbrel (etanercept) is a prescription drug used to treat certain inflammatory conditions. This drug can interact with certain medications and vaccines. For example, Enbrel can interact with infliximab ...

About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane ...

Glovadalen, a novel D1 receptor positive allosteric modulator, is linked to improve OFF time in patients with Parkinson’s ...

A recent Northwestern Medicine study has identified novel neural circuits modulated by the diabetes and obesity-management ...