Heart failure often develops after a heart attack because excessive collagen-based scar tissue forms during repair. While collagen is necessary to reinforce scars, disease and chronic inflammation can ...

Researchers at Karolinska Institutet and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant ...

Using computational tools and virtual screening, researchers at the Center for Redox Processes in Biomedicine (Redoxoma) have identified new inhibitors of the enzyme human 15-lipoxygenase-2 (h15-LOX-2 ...

A new method developed by researchers at KAIST and Chungnam National University could drastically streamline drug interaction testing—replacing dozens of traditional experiments with just one. The ...

A small-molecule inhibitor of the asparagine-cleaving enzyme AEP was associated with longer survival, reduced frailty, better cognition, and improved metabolic health in naturally aged mice, though ...

A new review in Plant Molecular Biology defines plant multifunctional inhibitors as a distinct class of double-headed defense ...

Please provide your email address to receive an email when new articles are posted on . Patients with advanced chronic kidney disease may benefit from use of angiotensin-converting enzyme inhibitors ...

The results of a preclinical study by lymphoma researchers at Weill Cornell Medicine suggest that an emerging class of anticancer drugs called EZH2 inhibitors may greatly enhance the potency of some ...

First publication reveals how roginolisib uniquely locks the cancer-driving enzyme PI3Kδ in an inactive state, differentiating the drug from ...