All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...
The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...
Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...
DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...
Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...
ASH1, Absent, small, or homeotic discs 1; CpG, 5′-Cyto- sine-phosphate-Guanine-3′ EZH, Enhancer of Zeste Homolog; GAS5, growth arrest-specific transcript 5; IFT80, Intraflagellar Transport 80; ...
Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports. This is the first detailed study ...
Salk Institute researchers find new mode of epigenetic targeting, showing for the first time that genetic sequences can direct new DNA methylation patterns in plants LA JOLLA (November 21, 2025)—All ...
Less than 2% of the genome codes for proteins; the rest, once called 'junk DNA', contains regulatory elements. Researchers ...