During oxidative stress, GAPDH is affected then enters the nucleus of neurons, where it affects protein turnover and leads to cell death, causing neurodegenerative loss. The anti-Parkinson's drug ...

Scientists are taking a closer look at the main breakdown product of aspirin, called salicylic acid, and its potential to treat neurodegenerative diseases, such as Alzheimer’s and Parkinson’s.

Researchers at Johns Hopkins have unraveled the molecular foundations of cocaine's effects on the brain, and identified a compound that blocks cravings for the drug in cocaine-addicted mice. The ...

Scientists are taking a closer look at the main breakdown product of aspirin, called salicylic acid, and its potential to treat Alzheimer’s and Parkinson’s. Salicylic acid binds to an enzyme called ...

A novel study reveals that targeting a single protein’s aggregation can dramatically reduce brain injury after stroke, potentially transforming how acute ischemic strokes are treated. Study: ...