Hypothalamic damage disrupts hunger and satiety regulation, causing rapid weight gain, which often responds poorly to ...

Hypothalamic obesity (HyOb) develops when brain damage or conditions like Prader-Willi syndrome disrupt the hypothalamus, impairing hunger and energy regulation. Traditional calorie-based weight-loss ...

A new therapy helps achieve a healthier BMI in people whose weight has become dysregulated following treatment for a brain tumor, a clinical trial has found.

How often do you think about your hypothalamus? Chances are that you never do. As compared to the rest of our brain, it is tiny—just the size of an almond. Yet it is our body's master control, ...

New research reveals how extracellular matrix (ECM) buildup in the brain’s hypothalamus leads to insulin resistance, paving the way for innovative therapies targeting obesity and diabetes. Study: ...

Phase III data supported setmelanotide's recent label expansion in acquired hypothalamic o ...

Researchers at EPFL and Lausanne University Hospital (CHUV), led by professors Grégoire Courtine and Jocelyne Bloch, have achieved a major milestone in the treatment of spinal cord injuries (SCI). By ...

Finn’s family once used alarms on the fridge and pantry. A new treatment changed that.

MC4R pathway restoration with daily subcutaneous setmelanotide achieved a −16.5% least-squares mean BMI change versus +3.3% with placebo at 52 weeks (P < .001). Clinically relevant response rates ...

Ovulatory dysfunction, including Polycystic ovary syndrome (PCOS) are among the most common causes of infertility in women. Caused by problems with the regulation of reproductive hormones, ovulation ...