Chronic Physical Effects and Health Care Utilization in Long-Term Ovarian Germ Cell Tumor Survivors: A Gynecologic Oncology Group Study Patients were selected according to the following criteria: ...

The other 10 to 15% of all chondrosarcomas are infrequent subtypes, such as dedifferentiated, myxoid, clear cell, and mesenchymal chondrosarcomas. 11,28 Mesenchymal chondrosarcoma is a high-grade ...

Two NADP-isocitrate dehydrogenase isoenzymes designated as NADP-IDH1 and NADP-IDH2 (EC 1.1.1.42) were identified in pea (Pisum sativum) leaf extracts by diethylaminoethyl-cellulose chromatography. The ...

Vorasidenib is an investigational oral, selective, highly brain-penetrant dual inhibitor of IDH1/2 enzymes. The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug ...

Somatic monoallelic single nucleotide variants in the genes that encode isocitrate dehydrogenase (IDH) 1 and 2 are found in a large subset of diffusely infiltrating gliomas and subsets of acute ...

Researchers are developing and testing new treatments for isocitrate dehydrogenase (IDH)-mutant gliomas, including targeted therapies and immunotherapies. These treatments may help improve survival ...

Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion–Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study Twenty-three patients received ...

A full-length cDNA (icdh-1) encoding a cytosolic NADP+-dependent isocitrate dehydrogenase (ICDH-1) from potato (Solanum tuberosum L.) has been isolated. Analysis of the deduced protein sequence ...

The isotrate dehydrogenase (IDH) inhibitors market sales is predicted to expand from US$ 1.7 billion in 2022 to US$ 39.16 billion in 2033, with a compound annual growth rate (CAGR) of 33% from 2023 to ...

Servier India, a research-driven pharmaceutical organization focused on oncology and specialty therapeutic areas in India, , has received a positive recommendation from the Subject Expert Committee ...