A computational model explains how place cells in the hippocampus can be recruited to form any kind of episodic memory, even when there's no spatial component. Nearly 50 years ago, neuroscientists ...

Memories are thought to be encoded in the brain as enduring physical and chemical changes, or engrams. Although recent technological advances have enabled substantial progress in our understanding of ...

Nearly 50 years ago, neuroscientists discovered cells within the brain's hippocampus that store memories of specific locations. These cells also play an important role in storing memories of events, ...

Both presenilin-1 or the less-studied presenilin-2 can act as the catalytic subunit of γ-secretase, the enzyme responsible for churning out Aβ peptides. A new study, published November 29 in Nature ...