Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...
Mitochondrial dysfunction in astrocytes is a driver of Parkinson’s disease (PD), but its upstream modulators are not well identified. Mendelian randomization and single-cell transcriptomic analysis ...
Does having high body fat in childhood only manifest in the blood at that time? Or does it leave a long shadow on proteins in ...
Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...
An integrated analysis of proteomic data from nearly 90,000 people, single-cell sequencing and molecular docking has identified seven high-confidence drug targets for premature ovarian insufficiency, ...
The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...
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