A foramen ovale is a hole in the heart. The small hole naturally exists in babies who are still in the womb for fetal circulation. It should close soon after birth. If it doesn’t close, the condition ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Studies to date have shown an association between the presence of patent foramen ovale and cryptogenic stroke in patients younger than 55 years of age. This association has not been established in ...

A “dose-response” relationship may exist between migraine and patent foramen ovale (PFO), according to a review published in Frontiers in Neurology. According to the American Heart Association, a PFO ...

A patent foramen ovale (PFO) is a hole in the heart that doesn’t close as expected after birth. Before a baby is born, they have a hole between the left and right sides of their heart. This hole, ...

A patent foramen ovale is an opening that some adults have between the top two chambers of their hearts. Everyone has this opening early in life, but it often seals during infancy. In some people, ...

Patent foramen ovale (PFO) is the most common congenital heart abnormality of fetal origin and is present in approximately ∼25% of the worldwide adult population. PFO is the consequence of failed ...