Tomosyn's tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction, incluiding their ability to engage in a form of plasticity The ...

Hormone therapies have played a major role in improving survival for patients with ER+ breast cancer [1]. By blocking or reducing estrogen’s impact, these treatments slow the cancer’s growth and help ...

The left panel shows the "tonic" neuron (stained green) innervating just one muscle on the right of the panel. In the next panel, one can see the phasic neuron (also stained green) connecting to more ...

Researchers at Ruhr University Bochum, Germany, identified a receptor that plays a crucial role in stress-induced motor ...

Real-world immune-related adverse events in patients with early triple negative breast cancer who received pembrolizumab. Prevention of sacituzumab govitecan (SG)-related neutropenia and diarrhea in ...

In this phase 3, multinational, randomized, double-blind trial, we examined the safety and efficacy of once-daily orforglipron at doses of 6 mg, 12 mg, or 36 mg, as compared with placebo (assigned in ...

Humans have about 400 odorant receptors (ORs), but scientists have had trouble finding ligands that match up with most of ...

New research addresses a gap in understanding how ketamine's impact on individual neurons leads to pervasive and profound changes in brain network function. A World Health Organization Essential ...

The versatility of the nervous system comes from not only the diversity of ways in which neurons communicate in circuits, but also their “plasticity,” or ability to change those connections when new ...