The development of leukemia is a complex, multistep process that is not fully understood. Although many leukemias harbor chromosomal translocations and additional mutations that drive oncogenic ...

This article starts by reviewing the differences between various measures of fitness, for example, individual fitness, absolute fitness, relative fitness and geometric mean fitness. Differences in ...

Wright's adaptive topography describes gene frequency evolution as a maximization of mean fitness in a constant environment. I extended this to a fluctuating environment by unifying theories of ...