Nanjing Deheng Pharmaceutical Technology Co. Ltd. and Nanjing Delova Biotech Co. Ltd. have discovered new sodium channel protein type 10 subunit α (SCN10A; Nav1.8) blockers reported to be useful for ...

Sodium channel blockers are medications that help reduce abnormal electrical activity in the heart. They can also lower the risk of severe complications such as stroke or sudden cardiac death. Sodium ...

Sodium channels — which transmit sensory information from neurons to the central nervous system — are logical targets for pain treatment. Nonselective sodium channel blockers can reduce pain, but they ...

Nat Clin Pract Neurol. 2008;4(3):159-169. Drug Primary clinical use Protective effect during administration in animal models? Effects of withdrawal in EAE Clinical study Phenytoin Treatment of ...

Hyundai Motor's U.S. unit, Chrysler-parent Stellantis and Delta Air Lines on Monday each announced they are among companies donating $1 million to President-elect Donald Trump's inaugural fund.

A novel, investigational NaV1.8 sodium channel blocker known as VX-548 reduced acute pain after abdominoplasty or bunionectomy at the highest dose, but not at lower doses, two phase II trials showed.

A new study adds to evidence which suggests treating breast cancer patients with sodium channel blockers could be a promising future treatment to prevent the spread of cancer during the gap between ...

Depending on the type of irregular heartbeat (arrhythmia), medication can help slow or regulate a person’s heartbeat. Doctors will assess symptoms to decide the best medication. Medications for ...

PHILADELPHIA -- An oral, non-addictive sodium channel blocker safely relieved moderate-to-severe acute pain following surgery, according to phase III data that could support regulatory approval.