Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 13 (March 30, 2021), pp. 1-12 (12 pages) Decades of work have demonstrated that messenger RNAs (mRNAs) ...

In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...

Generation LNP Advancements enhance potency and safety, expand delivery beyond the liver, and enable broader therapeutic ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

Neurodegenerative diseases are commonly adult-onset conditions characterized by degeneration of specific neuronal populations. Familial forms are caused by mutations in single genes, but most patients ...

The translation initiation factor eIF4E-binding protein-mediated regulation of protein translation by interfering with assembly of mRNA cap-binding complex eIF4F is well described in mammalian and ...