With the U.S. FDA’s accelerated green light for its DNA therapy targeting recurrent respiratory papillomatosis (RRP), backers of Inovio Pharmaceuticals Inc. began mulling the confirmatory trial and ...
BioWorld tracked 197 clinical trial updates in September 2026, more than double the 93 reported in August. Phase II accounted for the most readouts at 80, followed by phase III with 73 and phase I ...
Potassium-competitive acid blockers (P-CABs) reduce gastric acid secretion by inhibiting H+/K+ ATPase and have been proposed ...
Hefei Amvite Pharmaceutical Co. Ltd. and Hefei Industrial Pharmaceutical Institute Co. Ltd. have synthesized new growth hormone secretagogue (GHS) receptor agonists reported to be useful for the ...
H5N1 clade 2.3.4.4b emerged in 2020, causing significant outbreaks in poultry and cattle, and leading to multiple zoonotic infections in humans. Although the current risk of human-to-human ...
Oric Pharmaceuticals Inc. has disclosed new protein/nucleic acid degraders comprising a cereblon-binding moiety coupled to an androgen receptor-targeting moiety through a linker potentially useful for ...
Nimbus Selene Inc. has detailed new solute carrier family 15 member 4 (SLC15A4) inhibitors potentially useful for the treatment of gout, atherosclerosis, multiple sclerosis, psoriasis, rheumatoid ...
Previous findings from Indiana University and Northwestern University revealed that the inhibition of GABA aminotransferase (GABA-AT) produced analgesia in neuropathic and inflammatory models and ...
Chia Tai Tianqing Pharmaceutical Group Co. Ltd. has patented new thiazoloheteroaryl-containing compounds acting as DNA polymerase θ (POLθ, POLQ) inhibitors potentially useful for the treatment of ...
Researchers from Boehringer Ingelheim Pharmaceuticals Inc. and The Institute of Cancer Research reported the preclinical characterization of BI-1703880, a STING agonist, in several models of cancer.
Researchers at the University of Liège presented a PTK7-targeted gene therapy for glioblastoma that combines an anti-PTK7 nanobody (VHH-PTK7) with a recombinant adeno-associated viral (rAAV) vector to ...
Eos Senolytix Inc. has released early interim results from a study in aged rats of PTC-2105, a once-weekly, subcutaneously injected geropeptide from the Mitoxcel platform.
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