Firefighters responded to a house fire on East Jefferson street in Caledonia Minnesota early Wednesday evening.

Firefighters responded to a house fire on East Jefferson street in Caledonia Minnesota early Wednesday evening.

GENOA, Wis. (WXOW) - An RV is destroyed in a fire on Tuesday afternoon. The Genoa-Harmony Fire Department responded to the ...

UW-L Chancellor James Beeby joined us in studio talking about the upcoming semester at UW-La Crosse as well as some other ...

LA CROSSE, Wis. (WXOW) - Wisconsin and Minnesota residents will have the chance to fish without paying on January 18-19. Most ...

As temperatures dip, the Catholic Charities La Crosse Warming Center sees an increase in guests seeking warm shelter.

A man is arrested after losing control of his vehicle and crashing into a Holmen residence on Wednesday afternoon.

A warm front will be moving through the Coulee Region tonight, giving us chances for rain and/or wintry mix with breezy winds ...

Democrats have asked the Minnesota Supreme Court to intervene in a partisan power struggle that has roiled the start of the ...

Sean Duffy, Trump's pick for transportation secretary, said Boeing needs "tough love" during his confirmation hearing.

President Joe Biden is preparing to deliver a farewell address to the nation from the Oval Office. Watch live coverage here.

The DeForest Police Department, Occupational Safety and Health Administration and Dane County Medical Examiner's Office are ...