Recombinant human prourokinase is noninferior to alteplase in acute ischemic stroke, with symptomatic intracranial hemorrhage and major bleeding decreased.

Endovascular thrombectomy for medium-vessel occlusion stroke shows no benefit over usual care at 90 days and is linked to increased mortality, a multicenter trial finds.

The benefits and safety of mechanical thrombectomy (MT) in patients with prestroke disability, classified as modified Rankin Scale (mRS) score of 3 to 4, and anterior circulation stroke remain ...

We saw very encouraging reduction in lesion size based on the subjective MRI measure and also encouraging trends in functional improvement in the modified Rankin ... we start to scale this ...

Area under the receiver operating characteristic curve (AUC) analyses in the total cohort and pre-defined subgroups were performed to determine each tool’s prognostic value for good functional outcome ...

Using random effects meta-analysis, we evaluated the following outcomes: first-pass recanalization, Thrombolysis In Cerebral Infarction (TICI) 3 recanalization, TICI 2b/3 recanalization, favorable ...

Consecutive AIS patients owing to proximal cerebral major artery occlusion were included according to the following criteria: (1) age ≥ 18 years; (2) modified Rankin Scale (mRS) prior to the index ...

AIS: acute ischemic stroke; sICH, symptomatic intracranial hemorrhage; mRS, modified Rankin scale. Since this is a mathematical model, several assumptions were made to better reflect the natural ...

The modified Rankin Scale (mRS) was used to assess neurological disability on a scale from 0 (no symptoms) to 5 (full-time nursing required) at disease maximum and at the time of study MRI. Since ...