Background Antifibrotic (AF) therapy has been shown to potentially reduce the risk of lung cancer (LC) in patients with ...

Background Quadriceps maximal voluntary contraction (QMVC) reliably measures quadriceps muscle force and predicts mortality in chronic obstructive pulmonary disease (COPD). However, the minimal ...

Protein tyrosine phosphatase non-receptor type 2 (PTPN2) is a tyrosine phosphatase involved in T cell receptor signal transduction and cytokine response. Loss of function variants have previously been ...

8 Department of Respiratory Medicine at Royal Brompton Hospital, London, Chelsea & Westminster Hospital, and Imperial College, London, UK 9 Chelsea and Westminster Hospital, London, UK Correspondence ...

Background The EQ-5D, a generic health status questionnaire that is widely used in health economic evaluation, was recently expanded to the EQ-5D-5L to address criticisms of unresponsiveness and ...

Antileukotriene drugs are new therapeutic agents that have recently been approved for the treatment of asthma. Several cases of eosinophilic conditions including Churg-Strauss syndrome have been ...

Correspondence to Dr Alison M DeDent, 513 Parnassus Ave, HSE 1314, Box 0111, University of California San Francisco, San Francisco, California CA 94143, USA; alison.dedent{at}ucsf.edu ...

Introduction Air pollution is associated with increased asthma-related admission rates (Lancet, 2014;383(9928):1581–92). The impact of pollution on outcomes of monoclonal antibody (MAb) therapy in ...

Rationale Several randomised controlled trials support the provision of early pulmonary rehabilitation (PR) following hospitalisation for acute exacerbation of chronic obstructive pulmonary disease ...

Sex differences in outcome after endoscopic lung volume reduction (ELVR) in patients with emphysema: a retrospective analysis of the German Lung Emphysema Registry (LER e.V.) ...

1 Department of Respiratory Medicine, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK 2 NHLI Cardiovascular Sciences, Imperial College, Hammersmith Campus, London, UK ...