Thorax

Upstaging of screen-detected lung cancers during diagnostic assessment

A key outcome from lung cancer screening studies is the concept of ‘stage-shift’ seen in screen-detected cancers compared ...
Thorax

Frailty, comorbidity and survival comparisons between populations eligible for screening according to risk factor versus risk score criteria: results from the Yorkshir…

Background Lung cancer screening is effective for people at higher risk of the disease, but there is no international ...
Thorax

Airway microbiota in young people across four continents differ by country, asthma status and inflammatory phenotype

Background Asthma is an umbrella diagnosis encompassing distinct pathophysiological mechanisms. While a global problem, our ...
Thorax

Minimal important difference of quadriceps maximal voluntary contraction (QMVC) in COPD: a prospective cohort study

Background Quadriceps maximal voluntary contraction (QMVC) reliably measures quadriceps muscle force and predicts mortality in chronic obstructive pulmonary disease (COPD). However, the minimal ...
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Clinical impact of customised positive airway pressure (PAP) therapy interfaces (3DPiPPIn): a single site randomised controlled trial

Introduction Positive airway pressure (PAP) therapy is the recognised treatment for sleep disordered breathing (SDB), delivered via a tight-fitting face mask (interface). Conventional interfaces do ...
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Home-based rehabilitation for COPD using minimal resources: a randomised, controlled equivalence trial

4 The Nossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia Background Pulmonary rehabilitation is a cornerstone of care for COPD but uptake of traditional ...
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Physical rehabilitation interventions for adult patients during critical illness: an overview of systematic reviews

2 Centre for Human and Aerospace Physiological Sciences, King's College London, London, UK 3 Guy's & St Thomas’ NHS Foundation Trust and King's College London, National Institute of Health Research ...
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Mobile health pulmonary rehabilitation (m-PR): a randomised controlled equivalence trial

Background Mobile health (mHealth) is a novel model of care that may overcome barriers to pulmonary rehabilitation (PR) access. This study determined if mHealth PR was equivalent to centre-based PR ...
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Multidisciplinary, non-pharmacological breathlessness intervention service for patients with moderately severe to severe COPD: a randomised controlled trial

Background Chronic obstructive pulmonary disease (COPD) is an often-progressive respiratory disease associated with disabling breathlessness. Breathlessness intervention services (BIS), which coach ...
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Online First

Sex differences in outcome after endoscopic lung volume reduction (ELVR) in patients with emphysema: a retrospective analysis of the German Lung Emphysema Registry (LER e.V.) ...
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Rates of asthma exacerbations and mortality and associated factors in Uganda: a 2-year prospective cohort study

Data on asthma treatment outcomes in Africa are limited. 449 patients with asthma (age 5–93 years) in Uganda were followed up for 2 years to determine rates of exacerbations and mortality and ...
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Recurrent TB: a systematic review and meta-analysis of the incidence rates and the proportions of relapses and reinfections

Correspondence to Dr Larissa Otero, Facultad de Medicina, Universidad Peruana Cayetano Heredia, Lima 15102, Peru; larissa.otero{at}upch.pe Background A recurrent tuberculosis (TB) episode results from ...